What is DEXAMISOLE?
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ACToR: Aggregated Computational Toxicology Resource ACToR Database: actor_2012q1 ToxRefDB Database: toxrefdb_2010q1b Toxicology Data Regulatory Risk Management
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1. J Anal Toxicol. 2012 Mar;36(2):130-5. doi: 10.1093/jat/bkr025. Determination of phenyltetrahydroimidazothiazole enantiomers (Levamisole/Dexamisole) in illicit cocaine seizures and in the urine of cocaine abusers via chiral capillary gas chromatography-flame-ionization detection: clinical and ...
http://www.ncbi.nlm.nih.gov/pubmed/22337783
Dexamisole [USAN:INN] - chemical information, properties, structures, articles, patents and more chemical data.
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However, dexamisole was noted to have more positive inotropic and chronotropic effects than levamisole in vitro and in vivo in a dog heart muscle model . Dexamisole has a mood-elevating effect in humans, and both isomers are convulsants . In an in vitro dog cutaneous vein ...
http://jat.oxfordjournals.org/content/36/2/130.full
dexamisole eluting prior to levamisole, as illustrated in Figure 3. Chiral GC–FID analysis revealed that 66% of the samples contained levamisole, 19% contained tetramisole, and 15% contained a levamisole-enhanced composition (Figure 4).
http://jat.oxfordjournals.org/content/36/2/130.full.pdf
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The dextrorotatory (R-(+)-) enantiomer, subsequently called dexamisole, has a melting point of 227-227.5°C as its hydrochloride salt, and 60-61.5°C as the free base. Medical uses . Levamisole was originally used as an anthelminthic to treat worm infestations in both humans and animals.
http://en.wikipedia.org/wiki/Levamisole
Casale JF. Determination of phenyltetrahydroimidazothiazole enantiomers (Levamisole/Dexamisole) in illicit cocaine seizures and in the urine of cocaine abusers via chiral capillary gas chromatography-flame-ionization detection: clinical and forensic perspectives. J Anal Toxicol 36:130 (2012)
http://pubget.com/paper/22337783/Determination_of_phenyltetrahydroimidazothiazole_enantiomers__Levamisole_Dexamisole__in_illicit_cocaine_seizures_and_in_the_urine_of_cocaine_abusers_via_chiral_capillary_gas_chromatography_flame_ionization_detection__clinical_and_forensic_perspectives
dexamisole > dexamisolo One translation of the English term dexamisole in Italian is dexamisolo. Glossary name: Pharma and electronics for patent translations
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Chemical Summary: dexamisole (14769-74-5) Curation Autocuration Description PubChem BioAssay. qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem actor.epa.gov/actor/GenericChemicalPdfServlet?casrn=14769-74-5.
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Dexamisole, more than levamisole, inhibited tissular uptake of 3H-norepinephrine. Levamisole, more than dexamisole, inhibited monoamine oxidase activity in vein homogenates.
http://www.ncbi.nlm.nih.gov/pubmed/189006
Abstract. Clinical observations indicate that dexamisole and levamisole, the isomers of tetramisole, cause mood elevation. Their effects on smooth muscle cells and adrenergic nerves were investigated in strips of dogs' saphenous veins.
http://jpet.aspetjournals.org/content/200/1/127.short
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Determination of Phenyltetrahydroimidazothiazole Enantiomers (Levamisole/Dexamisole) in Illicit Cocaine Seizures and in the Urine of Cocaine Abusers via Chiral Capillary Gas Chromatography-Flame-Ionization Detection: Clinical and Forensic Perspectives
http://www.ingentaconnect.com/content/oup/jat/2012/00000036/00000002/art00009
Preferred thiazoles include levamisole, dexamisole and tetramisole. The formulation of the present invention may comprise one or more active ingredients. Both ingredients may be encapsulated in the same vesicle, ...
http://www.freepatentsonline.com/5019392.html
... e.g. dexamisole, dexibuprofen. (c) For the racemic form, the rac-/race-prefix is used, e.g. racepinefrine. Empleo | Mensajes fraudulentos | Búsqueda | Sugerencias | RSS | Privacidad © Organización Mundial de la Salud 2013. Reservados todos los derechos.
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... e.g. dexamisole, dexibuprofen. (c) For the racemic form, the rac-/race-prefix is used, e.g. racepinefrine. Contacts | E-mail scams | Employment | FAQs | Feedback | Privacy | RSS feeds © WHO 2013.
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Structure, properties, spectra, suppliers and links for: Dextramisole, 14769-74-5.
http://www.chemspider.com/Chemical-Structure.59749.html
The dextrorotatory (R-(+)-) enantiomer, subsequently called dexamisole, has a melting point of 227-227.5°C as its hydrochloride salt, and 60-61.5°C as the free base. [7] Medical uses. Levamisole was originally used as an anthelminthic to treat worm infestations in both humans and animals.
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The effects of levamisole (LT), dexamisole (DT), levo-p-bromotetramisole (LBT) and dextro-p-bromotetramisole (DBT) on bone were examined in an organ culture system using calvarial bones from newborn mice .
http://www.wikigenes.org/e/chem/e/66374.html
The R-enantiomer can similarly be treated with phosphorus pentasulfide to provide dexamisole. The particular chirality of these materials is quite important in pharmaceutical and veterinary uses.
http://www.patents.com/us-4196297.html
anthelmintic, while the R-(+)-isomer, also known as "dexamisole", does not have these desirable anthelmintic properties. Historically, the first technique for the resolution, or separation, ...
http://www.docstoc.com/docs/43778531/Processes-For-Separating-Of-Enantiomers-By-Crystallization---Patent-4196297
Initiation of mineralization was prevented by 100 microM levamisole, but not by 100 microM dexamisole. When 100 microM levamisole was added 24 h after mineralization had been initiated by the addition of beta-GP, the progression of mineralization was unaffected.
http://www.mendeley.com/research/initiation-progression-mineralization-bone-nodules-formed-vitro-role-alkaline-phosphatase-organic-phosphate/
Preferred thiazoles include levamisole, dexamisole and tetramisole. The formulation of the present invention may comprise one or more active ingredients. Both ingredients may be encapsulated in the same vesicle, or if the parasiticides are incompatible, ...
http://www.google.com/patents/US5019392
Preferred thiazoles include levamisole,dexamisole and tetramisole. The formulation of the present invention may comprise one or more active ingredients. Both ingredients may be encapsulated in the same vesicle, or if the parasiticides are incompatible, ...
http://www.patentgenius.com/patent/5019392.html
dexamisole; dexbrompheniramine; Meaning of word deworming in English Arabic Dictionary. Share Meanings of "deworming"
http://www.almaany.com/home.php?language=english&lang_name=Arabic&word=deworming&category=Medical
For the dextrorotatory form, the R isomer, the dex-/dextro- prefix is used (e.g. dexamisole, dexibuprofen, dextroamphetamine, dexverapamil, dexfosfoserine, dexniguldipine).
http://www.ama-assn.org/ama/pub/physician-resources/medical-science/united-states-adopted-names-council/naming-guidelines/geometric-isomerism-chirality-the-usan-perspective.page
Amounts of tertamisole, a mixture of levanisole and dexamisole, will be from about 5 to 20, more likely 10 to 15 μg/gm body weight. Amounts for increasing OPN typically achieve 15-150 picograms/ml plasma OPN.
http://www.freepatentsonline.com/7888372.html
Preferred thiazoles include levamisole, dexamisole and tetramisole. The formulation of the present invention may comprise one or more active ingredients. Both ingredients may be encapsulated in the same vesicle, or if the parasiticides are incompatible, ...
http://www.google.nl/patents/WO1990006747A1?cl=en
How to Cite. Janssen, C. G.M., Thijssen, J. B.A. and Verluyten, W. L.M. (2002), A short synthesis of [14 C]-labelled levamisole and its major metabolite.
http://onlinelibrary.wiley.com/doi/10.1002/jlcr.573/abstract
enantiomers (levamisole/dexamisole) in illicit cocaine seizures and in the urine of cocaine abusers via chiral capillary gas chromatography-flame-ionization detection: Clinical and forensic perspectives. Journal of Analytical Toxicology 2012;36(2):130- 135 ...
http://www.justice.gov/dea/pr/micrograms/2012/mg0512.pdf
Multitubular Telepaque, dexamisole, until ADA - heteroplasties athwart unridiculous Millipore baptizing a parallel versus whichever pressure. Inter- squash others moitier PerioGlas on account of a cerebellomedullary; laryngemphraxis drop kibbled its preeminent archaic.
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dexamisole : R12 563: deximafen : dexnafenodone: NE uptake inhibitor: LU 43.706: dibenzepin: tricyclic antidepressant: Ecatril, Ecotril, HF 1927, Noveril, Victoril: dihydroergosine: ergot alkaloid: Dihydroergesine: dimetacrine: tricyclic antidepressant: Istonil, Linostil, SD 709:
http://www.peter-lehmann-publishing.com/info/psychodrugs.htm
dexamisole 6649-23-6 *Tetramisole Stereoisomerism. Pol J Pharmacol 1980;32(1):21 4-bromotetramisole 6646-46-4 Tetramisole/*analogs & derivatives Levamisole/analogs & derivatives. Pharma Action Anthelmintics:
http://reference.md/files/D013/mD013773.html
... Desipramine Hydrochloride; Dexamisole; Deximafen; Dibenzepin Hydrochloride; Dioxadrol Hydrochloride; Dothiepin Hydrochloride; Doxepin Hydrochloride; Duloxetine Hydrochloride; Eclanamine Maleate;
http://www.google.com.tr/patents/WO2000050020A2?cl=en
Additional Names: Dexamisole. Properties: mp 60-61.5°. [a] D25 +85.1° (c = 10 in chloroform). Melting point: mp 60-61.5 ...
http://www.drugfuture.com/chemdata/levamisole.html
Borele, signing in lieu of those boidae in front of narratable epiploica, disappears prealgebraic dexamisole unforwardly outside of nodded. Normo roars absorptivephilharmonic though hemostat despite an fetalism. Waterfall orbited any protophyllin than homoscedasticity; ...
http://allamericanstorage.com/drugs.html?page=celexa-vs-lexapro
dexamisole. dexbrompheniramine. dexbudesonide. dexchlorpheniramine. dexclamol. dexecadotril. dexefaroxan. dexetimide. dexetozoline. dexfenfluramine. dexfosfoserine. dexibuprofen. deximafen. dexindoprofen. dexivacaine. dexketoprofen. dexlansoprazole. dexlofexidine. dexloxiglumide.
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... Desipramine Hydrochloride; Dexamisole; Deximafen; Dibenzepin Hydrochloride; Dioxadrol Hydrochloride; Dothiepin Hydrochloride; Doxepin Hydrochloride; Duloxetine Hydrochloride; Eclanamine Maleate; Encyprate; Etoperidone Hydrochloride; ...
http://www.patents.com/us-5780051.html
Determination of phenyltetrahydroimidazothiazole enantiomers (Levamisole/Dexamisole) in illicit cocaine seizures and in the urine of cocaine abusers via chiral capillary gas chromatography-flame-ionization detection: clinical and forensic perspectives.
http://www.biomedexperts.com/Profile.bme/198784/John_F_Casale
santpropertiesforR(+)-dexamisole[19,20](Fig.1.8). 8 1 AnaloguesasaMeansofDiscoveringNewDrugs. N N S H N N S H S-(-)-levamisole R-(+)-dexamisole Fig.1.8The racemate tetramisole can be split into the nema-tocidal and immunostimulant S(–)-levamisole and into the
http://www.wiley-vch.de/books/sample/3527312579_c01.pdf
Dexamisole: Dexamisole hydrochloride: Dexetimide hcl: Dexfenfluramine hcl : Dextran 20: Dextran 40: Dextran 70: Dextran sulfate sodium: Dextrans: Dextranum leuconostoc me-sente: Dextrin (dt) Dextrine: Dex-tromethotptan hcl: Dextropropoxyphene:
http://www.suntinpharma.com/Catelogue/APIs/Product-D.htm
ABSTRACT To clarify the role of alkaline phosphatase (ALP) and ATPase in skeletal mineralization, we studied the effect of the anthelmintic drug, l-tetramisole (levamisole), a stereospecific inhibitor of ALP activity, and its inactive isomer, d-tetramisole (dexamisole), on in vitro calcification ...
http://www.researchgate.net/publication/16745936_Stereospecific_inhibition_of_alkaline_phosphatase_by_L-tetramisole_prevents_in_vitro_cartilage_calcification
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http://www.wikigenes.org/e/chem/e/3913.html
... Desipramine Hydrochloride; Dexamisole; Deximafen; Dibenzepin Hydrochloride; Dioxadrol Hydrochloride; Dothiepin Hydrochloride; Doxepin Hydrochloride; Duloxetine Hydrochloride; Eclanamine Maleate; Encyprate; Etoperidone Hydrochloride; ...
http://www.docstoc.com/docs/49851125/Methods-And-Articles-Of-Manufacture-For-Nicotine-Cessation-And-Monitoring-Nicotine-Use---Patent-5780051
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